-- Preface. -- Part I: Introduction to free radicals. -- Free radical chemistry. -- Part II: Reactive species in tissues. -- Exercise and oxygen radical production by muscle. -- Exercise and xanthine oxidase in the vasculature: -- superoxide and nitric oxide interactions. -- Part III: Oxidative stress: Mechanisms and manifestations. -- Chemical bases and biological relevance of protein oxidation. -- Oxidative DNA damage in exercise. -- Part IV: Antioxidant defenses. -- Physiological antioxidants and exercise training. -- Antioxidants and physical exercise. -- Part V: Nutrition. -- Dietary sources and bioavailability of essential and nonessential -- antioxidants. -- Vitamin E. -- Part VI: Cellular and molecular mechanisms. -- Biological thiols and redox regulation of cellular induced signaling. -- Regulation and deregulation of vascular smooth muscle cells by -- reactive oxygen species and by &agr;-tocopherol. -- Part VII: Analytical methods. -- Oxidative stress indices: analytical aspects and significance. -- Noninvasive measures of muscle metabolism. -- Part VIII: Environmental factors. -- Air pollution and oxidative stress. -- Oxidants in skin pathophysiology. -- Part IX: Organ functions. -- Muscle fatigue: mechanisms and regulation. -- Influence of exercise-induced oxidative stress on the -- central nervous system. -- Part X: Aging. -- Oxidants and aging. -- Molecular mechanisms of oxidative stress in aging: free radicals, -- aging, antioxidants and disease. -- Part XI: Disease processes. -- Oxidative stress, antioxidants and cancer. -- Hypoxia, oxidative stress and exercise in rheumatoid arthritis. -- Index of authors. -- Subject index.Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress.

The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes.

This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience. Menos

-- Preface. -- Part I: Introduction to free radicals. -- Free radical chemistry. -- Part II: Reactive species in tissues. -- Exercise and oxygen radical production by muscle. -- Exercise and xanthine oxidase in the vasculature: -- superoxide and nitric oxide interactions. -- Part III: Oxidative stress: Mechanisms and manifestations. -- Chemical bases and biological relevance of protein oxidation. -- Oxidative DNA damage in exercise. -- Part IV: Antioxidant defenses. -- Physiological antioxidants and exercise training. -- Antioxidants and physical exercise. -- Part V: Nutrition. -- Dietary sources and bioavailability of essential and nonessential -- antioxidants. -- Vitamin E. -- Part VI: Cellular and molecular mechanisms. -- Biological thiols and redox regulation of cellular induced signaling. -- Regulation and deregulation of vascular smooth muscle cells by -- reactive oxygen species and by &agr;-tocopherol. -- Part VII: Analytical methods. -- Oxidative stress indices: analytical aspects and significance. -- Noninvasive measures of muscle metabolism. -- Part VIII: Environmental factors. -- Air pollution and oxidative stress. -- Oxidants in skin pathophysiology. -- Part IX: Organ functions. -- Muscle fatigue: mechanisms and regulation. -- Influence of exercise-induced oxidative stress on the -- central nervous system. -- Part X: Aging. -- Oxidants and aging. -- Molecula... Mostrar Tudo